The light bulb went off for co-founder Daniel Uzbelger Feldman when he was performing a challenging dental procedure to retrieve/bypass a separated instrument fragment left on a patient’s molar tooth during a root canal. Dr. Uzbelger Feldman still remembers his frustration and more importantly, the patient’s suffering, after three unsuccessful attempts of more than one hour each to retrieve the fragment. Since necessity is the mother of invention, he tried to find an alternative way to visualize these procedures during procedures instead of before and after due to the limitations of existing x-ray imaging technologies. He researched and discovered live imaging technologies were limited to the medical field. After comprehensive research, trial and error and by incorporating technologies used in ultra high definition digital cameras, it was feasible to achieve a higher image resolution, frame rates and lower radiation dose.
These findings formed the basis of Real Time Imaging Technologies that now will be commercialized for dental and medical imaging use for enhanced patient care as well as for large format wave-front sensing advanced adaptive optics applications.
By the first time in dental history, his other research area of expertise has showed evidence of the cervical plexus nerve implication in dental anesthesia failures and cardiac jaw pain which lead to the development of an improved intraoral cervical plexus anesthetic technique. These efforts have guided to the accessory innervation theory substantiation in dental anesthesia. Over 20 years of experience innovating in this field helped him to develop NeoCaine, the next generation of local anesthetic which buffers within the cartridge, doesn't sting, has a rapid onset, longer duration and better aftertaste.
Comprises the next generation of high quantum efficiency microlens-based and back illuminated flat panel detectors, large format adaptive optics wave-front sensing, dental imaging sensors and low dose x-ray sources resulting in significant dose reduction, higher resolution and dynamic/live visualization
Mr. Sinsheimer is the founder of Medtech Catalyst, which has founded or co-founded several medical and dental device companies. He is co-founder and Chairman of Mobius Imaging, LLC as well as the co-founder and CEO of Cardan Robotics. Prior to that, Mr. Sinsheimer has had various key management roles as President of Integrated Marketing Concepts, a consulting firm advising healthcare product companies; VP of Marketing and Strategic Planning for the Straumann Company, a dental implant company that grew to several hundred million in revenue; and Marketing Manager at Pfizer, Inc. Mike holds an MHA from the University of North Carolina Gillings School of Global Public Health and an MBA from the Stern School of Graduate Business at New York University.
Daniel has 23 years of experience in dentistry; as a clinician, entrepreneur and in Academia in two different countries. He is the inventor of the first-ever microlens / back-illuminated CMOS-based low-dose digital video imaging device for dentistry / low-dose ultra high definition flat panel detector / large format adaptive optics wave-front sensor and is the author of a seminal work on the comparison of existing dental imaging technologies to medical fluoroscopes. Dr. Uzbelger has put together device development, testing and FDA clearance proposals as well as strategic partnership opportunities and the RTI Tech management team. In 2014, he was granted with the Medical Device & Diagnostic Industry Dare-to-Dream Medtech Design Challenge Reader's Choice Award. In 2013, he was the recipient of the William H. Rollins Award granted by the American Academy of Oral & Maxillofacial Radiology. In addition, his team has won 3 consecutive awards at Temple University business plan competition series including the first prize in science and technology in the business plan competition.
Design and characterization of NeoCaine is also on its way through strategic partnerships he has established.
Uzbelger Feldman D, Yang J. Milliamperes settings and image noise reduction through back illumination and adaptive filtration. Abstract Book, 66th Annual Session of American Academy of Oral & Maxillofacial Radiology, Indianapolis, IN, 10/01/2015.
Uzbelger Feldman D., Panchal P.M., Yang J. Resolution and Dose Rates Comparison among Fluoroscopy, Digital/Film-Based Intraoral Radiography and CBCT Scan, Abstract Book of the 61th Annual Meeting of American Academy of Oral & Maxillofacial Radiology, San Diego, California, 2010.
Kim S, Uzbelger Feldman D, Yang J. A Systematic Review of the Cervical Plexus Accessory Innervation and Its Role in Dental Anesthesia. Journal of Anesthesia History. Journal of Anesthesia History 2 (2016) 79–84.
Mistry AR, Uzbelger Feldman D, Yang J, Ryterski E. Low Dose X-Ray Sources and High Quantum Efficiency Sensors: The Next Challenge in Dental Digital Imaging?. Radiology Research and Practice, vol. 2014, Article ID 543524, 7 pages, 2014. doi:10.1155/2014/543524.
Uzbelger Feldman D, Yang J, Susin C. A Systematic Review for the Uses of Fluoroscopy in Dentistry. Chin J Dent Res. 2010 Jun;13(1):23-29.
Bitner, D. P., Uzbelger Feldman, D., Axx, K. and Albandar, J. M. (2015), Description and evaluation of an intraoral cervical plexus anesthetic technique. Clin. Anat., 28: 608–613.
Lin K, Uzbelger Feldman D, Barbe MF. Transverse cervical nerve: Implications for dental anesthesia. Clin Anat. 2013 Sep;26(6):688-92.
Uzbelger-Feldman D, Bitner D, Axx KT, Chattopadhyay A. Effectiveness of supplemental cervical plexus anesthetic technique for achieving anesthesia in mandibular molars with irreversible pulpitis. J Endod. 2007; 33(3):345.
Uzbelger Feldman D, Mistry AR, Yang J. Radiation exposure and image resolution testing of a low-dose x-ray imaging. Abstract Book of the 64th Annual Meeting of American Academy of Oral & Maxillofacial Radiology, Beverly Hills, California, 2013.
Uzbelger D. Comparison between Medical Fluoroscopy, Digital Dental Imaging and Intraoral Radiography. IADR. J Dent Res 2005; 84; 701.
Kim S., Uzbelger Feldman D., Yang J. A systematic review of the cervical plexus nerve implications in dental anesthesia. Research Day Poster, Temple University Kornberg School of Dentistry, April 2015.
Uzbelger Feldman D, Bitner D, Axx K, Chattopadhyay A, Stevens R, Esposito J. Evaluation and Description of an Intraoral Cervical Plexus Anesthetic Technique (ICPAT). Research Day Poster, Temple University Kornberg School of Dentistry, 2009.